Loved fat kidney health is threatened? Kidney is self-evident the importance of our bodies, some fat people would have the body fat, fat is also very fond of fat meat, which adds to the burden on the kidneys, the kidneys are injured.
Recently, a research report of the expert pointed out that high-fat diet will not only increase kidney patients have kidney damage, kidney damage also lead to healthy people.
Rats fed high fat diet consisting of 4% cholesterol and 1% sodium cholate, the establishment of high-fat model of the experimental study. It was found that rats fed high-fat diet for 8 weeks significantly increased urinary protein, increased blood lipids, especially serum total cholesterol and LDL cholesterol. This confirms that high-fat diet can cause damage to healthy kidneys.
Further studies showed that, after feeding high-fat diet, along with elevated blood lipids, nitric oxide excretion in rat urine increased significantly, nitric oxide synthase in the kidney enhanced; high-fat diet rats in vivo increase in superoxide ion, superoxide ion in the kidney has also increased; nitric oxide and superoxide anion react to generate cells with the toxic effects of the peroxynitrite. A series of findings suggest that fat diet cause kidney damage possible mechanisms: nitric oxide and react with the superoxide ion in the renal tissue to generate the cells of the kidney to the toxic effects of peroxynitrite, resulting in cell apoptosis. Nitric oxide increased clearance, and proteinuria of nitric oxide synthase expression and nitric oxide increase may lead to glomerulosclerosis and tubular interstitial renal damage via apoptosis. In the study, they also found that nitric oxide synthesis inhibitor prevents glomerular mesangial cells dissolve and prevent proteinuria and reduce glomerular transforming growth factor β expression and the accumulation of extracellular matrix and prevent glomerulosclerosis.
The study emphasized that, where there are patients with renal impairment, hyperlipidemia appears to be lipid-lowering therapy, but also to the control diet, dietary adjustments according to renal damage. In general, patients with kidney disease should be as much as possible with a light diet Eat less high-fat diet has a protective effect on renal damage.
A long, healthy Xiaobian reminder: In order to develop healthy eating habits, we need to do all aspects of life. Loose lips, start with the mouth, in order to stay away from the disease to a healthy body, we should always pay attention to how a healthy diet. To learn more about healthy eating, please pay attention to a long healthy diet net channel.